Updated weekly with official CMS data

    NADAC Pricing Lookup for Independent Pharmacies

    Check the reimbursement before you submit the claim — spot payments that fall below cost. Free NADAC lookup by drug name or NDC, updated weekly from CMS.

    Weekly NADAC Price Movers

    Top 10 biggest NADAC price increases and decreases, ranked by percent change.

    Understanding NADAC Price Changes

    The National Average Drug Acquisition Cost (NADAC) is updated weekly by CMS, typically every Wednesday. These price changes reflect shifts in what pharmacies actually pay to acquire medications from wholesalers and manufacturers. Monitoring the biggest movers each week helps independent pharmacies stay ahead of cost fluctuations that directly impact margins.

    Why Do NADAC Prices Change?

    Price swings can result from manufacturer price adjustments, supply chain disruptions, generic competition entering the market, or changes in wholesale acquisition costs reported by pharmacies in the NADAC survey. Large increases may signal supply shortages, while significant decreases often indicate new generic alternatives becoming available.